LEO Pharma’s Adtralza (tralokinumab) Receives the Health Canada’s Approval for the Treatment of Atopic Dermatitis
Shots:
- Health Canada has approved Adtralza for adolescents aged 12-17yrs. with sev. AD whose disease is not adequately controlled with topical prescription therapies or those therapies are not advisable
- The approval was based on the P-III trial (ECZTRA 6) results evaluating Adtralza (150/300mg) monotx. with/out topical corticosteroids vs PBO in 289 adolescents. The recommended dosage is 600mg loading dose, followed by 300mg, EOW
- The trial met its 1EPs @16wk. as measured by an IGA score of clear or almost clear skin (IGA 0/1), 75% improvement in EASI score (EASI-75) & the trial also met its 2EPs i.e., reduction in itch with ≥4-point improvement in adolescent WP-NRS from baseline. Adtralza is a human mAb that binds to & inhibits IL-13 cytokine
Ref: Newswire | Image: Leo Pharma
Related News:- LEO’s Adtralza Receives EC's Approval for the Treatment of Moderate to Severe Atopic Dermatitis
Click here to read the full press release
Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.